Serveur d'exploration Chloroquine

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Proceedings of the British Toxicology Society Autumn Meeting Keble College, Oxford 12-14 September 1999

Identifieur interne : 002644 ( Main/Exploration ); précédent : 002643; suivant : 002645

Proceedings of the British Toxicology Society Autumn Meeting Keble College, Oxford 12-14 September 1999

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RBID : ISTEX:091427BA6A552C29F2513FC23583207B535CA46D

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Url:
DOI: 10.1191/096032799678839626


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Le document en format XML

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<term>Abdomen skin</term>
<term>Abstracts localization</term>
<term>Adaptive response</term>
<term>Additional immunostaining</term>
<term>Adduct</term>
<term>Adipose tissue</term>
<term>Aldehyde</term>
<term>Aldehyde metabolising enzymes</term>
<term>Alderley park</term>
<term>Ames</term>
<term>Amine</term>
<term>Anaemia</term>
<term>Andrews</term>
<term>Animal death</term>
<term>Animal model</term>
<term>Animal studies</term>
<term>Aplasia</term>
<term>Aplastic</term>
<term>Aplastic anaemia</term>
<term>Apoptosis</term>
<term>Aryl hydrocarbon receptor</term>
<term>Assay</term>
<term>Barrier creams</term>
<term>Beecham</term>
<term>Benoxaprofen</term>
<term>Best poster presentation</term>
<term>Bile canalicular plasma membrane</term>
<term>Bioassay</term>
<term>Biol chem</term>
<term>Biological sciences</term>
<term>Biomedical</term>
<term>Biomedical sciences</term>
<term>Biomedical sciences department</term>
<term>Blast analysis</term>
<term>Blood changes</term>
<term>Blood values</term>
<term>Body weight</term>
<term>Bugelski</term>
<term>Butadiene monoepoxide</term>
<term>Cacid metabolites</term>
<term>Calc</term>
<term>Cald</term>
<term>Caloric restriction</term>
<term>Canine purkinje fibres</term>
<term>Carcinogen</term>
<term>Carcinogenicity</term>
<term>Cdna</term>
<term>Cdna microarray data</term>
<term>Cdna microarrays</term>
<term>Cell division</term>
<term>Cell proliferation</term>
<term>Cell viability</term>
<term>Charcoal trap</term>
<term>Chem</term>
<term>Chemical risk assessment</term>
<term>Chemical safety</term>
<term>Chemical treatments</term>
<term>Chenspm</term>
<term>Chloroquine</term>
<term>Chronic bone marrow aplasia</term>
<term>Chronic hypoplastic marrow failure</term>
<term>Cinnamyl alcohol</term>
<term>Cisapride</term>
<term>Clinical pharmacology</term>
<term>Clinical pharmacology group</term>
<term>Compensatory tissue repair</term>
<term>Compound</term>
<term>Constitutive androstane mediates</term>
<term>Contact sensitizer</term>
<term>Control group</term>
<term>Current study</term>
<term>Cynomolgus monkey</term>
<term>Cyp2b genes</term>
<term>Cytochrome</term>
<term>Cytotoxicity</term>
<term>Cytotoxicity assay</term>
<term>Dapi staining</term>
<term>Dehp</term>
<term>Different studies</term>
<term>Differential gene expression</term>
<term>Differentially</term>
<term>Diffusion cells</term>
<term>Dnhp</term>
<term>Dos</term>
<term>Dose</term>
<term>Dose response</term>
<term>Dosing regimen</term>
<term>Drug metabolizing enzymes</term>
<term>Dunkin hartley guinea pigs</term>
<term>Electrical stimulation</term>
<term>Electrophoresis investigation</term>
<term>Environmental health criteria</term>
<term>Environmental pollutants</term>
<term>Enzyme</term>
<term>Epithelial cells</term>
<term>Erythromycin</term>
<term>Erythromycin liver toxicity</term>
<term>Ester</term>
<term>Ethylene dibromide</term>
<term>Experimental model</term>
<term>Exposure limits</term>
<term>False positives</term>
<term>Female mice</term>
<term>Final outcome</term>
<term>First step</term>
<term>Flavouring</term>
<term>Flavouring compounds</term>
<term>Fmollmg protein</term>
<term>Food additives</term>
<term>Frythe</term>
<term>Further studies</term>
<term>Gene</term>
<term>Gene expression</term>
<term>Glucuronidation</term>
<term>Good toxicology</term>
<term>Growth factor</term>
<term>Guidance values</term>
<term>Guinea pigs</term>
<term>Haematological results</term>
<term>Hair follicles</term>
<term>Hepatic</term>
<term>Hepatic failure</term>
<term>Hepatocarcinogenesis</term>
<term>Hepatocytes</term>
<term>Hepatotoxicity</term>
<term>Heterocyclic</term>
<term>Heterocyclic amine metabolism</term>
<term>Heterocyclic amines</term>
<term>High doses</term>
<term>Higher liver injury</term>
<term>Hotchkiss</term>
<term>Hour period</term>
<term>Human cells</term>
<term>Human health</term>
<term>Human intestine</term>
<term>Human liver microsome bank</term>
<term>Human placenta slices</term>
<term>Human skin</term>
<term>Human variability</term>
<term>Humans</term>
<term>Hypolipidemic drugs</term>
<term>Imperial college school</term>
<term>Individual cdna fragments</term>
<term>Inhibitor</term>
<term>Interindividual differences</term>
<term>International programme</term>
<term>Interspecies</term>
<term>Interspecies differences</term>
<term>Interval prolongation</term>
<term>Intestine</term>
<term>Joint winner</term>
<term>Kupffer cells</term>
<term>Laboratory animals</term>
<term>Large intestine</term>
<term>Large number</term>
<term>Late stage</term>
<term>Lauric acid</term>
<term>Light microscopy</term>
<term>Liver</term>
<term>Liver growth</term>
<term>Liver injury</term>
<term>Liver regeneration</term>
<term>Liver toxicity</term>
<term>Liver volume</term>
<term>Magnetic resonance imaging</term>
<term>Major component</term>
<term>Male rats</term>
<term>Male sprague dawley rats</term>
<term>Mammalian cells</term>
<term>Mansfield road</term>
<term>Marrow</term>
<term>Marrow cell counts</term>
<term>Marrow depression</term>
<term>Medical school</term>
<term>Mehendale</term>
<term>Melqx</term>
<term>Metabolic</term>
<term>Metabolic fate</term>
<term>Metabolic parameters</term>
<term>Metabolism</term>
<term>Microsome</term>
<term>Mismatch repair</term>
<term>Mitochondrial damage</term>
<term>Molecular biology</term>
<term>Molecular dynamics</term>
<term>Molecular level</term>
<term>Molecular mechanism</term>
<term>Molecular mechanisms</term>
<term>Molecular toxicology</term>
<term>Molecular toxicology group</term>
<term>Mouse</term>
<term>Mouse hepatocytes</term>
<term>Mouse liver</term>
<term>Mouse liver microsomes</term>
<term>Mouse skin</term>
<term>Mrna</term>
<term>Mrna species</term>
<term>Nasal</term>
<term>Nasal cavities</term>
<term>Nasal cavity</term>
<term>Nasal passages</term>
<term>Negligible risk</term>
<term>Nongenotoxic carcinogens</term>
<term>Nuclear receptors</term>
<term>Nucleotide excision repair</term>
<term>Oral gavage</term>
<term>Oxazolone</term>
<term>Oxidative stress</term>
<term>Oxidative stress agents</term>
<term>Parent compound</term>
<term>Partial hepatectomy</term>
<term>Pathway</term>
<term>Pbpk model</term>
<term>Percutaneous</term>
<term>Percutaneous absorption</term>
<term>Percutaneous penetration</term>
<term>Peripheral blood changes</term>
<term>Peroxisome</term>
<term>Peroxisome hepatocarcinogenesis</term>
<term>Peroxisome proliferators</term>
<term>Pharmaceutical</term>
<term>Pharmacol</term>
<term>Pharmacology</term>
<term>Phototoxic hazard</term>
<term>Phthalate</term>
<term>Phthalate esters</term>
<term>Physostigmine</term>
<term>Physostigmine sulphate</term>
<term>Placenta</term>
<term>Placenta slices</term>
<term>Polyamine</term>
<term>Polyamine analogues</term>
<term>Polyamine catabolic enzymes</term>
<term>Ppara</term>
<term>Preapplied pyrazole</term>
<term>Preclinical species</term>
<term>Preliminary experiments</term>
<term>Present study</term>
<term>Presurgery liver volume</term>
<term>Proliferators</term>
<term>Protective effect</term>
<term>Protein adducts</term>
<term>Protein complement</term>
<term>Protein level</term>
<term>Protein synthesis</term>
<term>Purkinje fibres</term>
<term>Rat</term>
<term>Reactive metabolite</term>
<term>Reactive metabolites</term>
<term>Receptor</term>
<term>Receptor fluid</term>
<term>Regeneration</term>
<term>Regulatory view</term>
<term>Renwick</term>
<term>Renwick uncertainty factors</term>
<term>Repair enzymes</term>
<term>Repair process</term>
<term>Repair systems</term>
<term>Reporter gene activity</term>
<term>Resonance imaging</term>
<term>Resveratrol</term>
<term>Reversible reticulocytopenia</term>
<term>Rhesus monkey</term>
<term>Risk assessment</term>
<term>Rodent</term>
<term>Rodent carcinogens</term>
<term>Safety assessment</term>
<term>Safety margins</term>
<term>Salmonella typhimurium</term>
<term>Same conditions</term>
<term>Sebaceous glands</term>
<term>Sensitive animal species</term>
<term>Several drugs</term>
<term>Severe tyrosinemia</term>
<term>Significant decrease</term>
<term>Significant differences</term>
<term>Significant effect</term>
<term>Significant increase</term>
<term>Significant reduction</term>
<term>Silver grains</term>
<term>Skin lesions</term>
<term>Skin models</term>
<term>Small intestine</term>
<term>Smithkline</term>
<term>Smithkline beecham pharmaceuticals</term>
<term>Smooth endoplasmic reticulum</term>
<term>Sodium valproate</term>
<term>Southampton</term>
<term>Species differences</term>
<term>Sprague dawley</term>
<term>Statistical analysis</term>
<term>Statistical significance</term>
<term>Strain differences</term>
<term>Stratum corneum</term>
<term>Subtractive hybridisation</term>
<term>Surface area</term>
<term>Surrey</term>
<term>Survival factors</term>
<term>Target genes</term>
<term>Test compound</term>
<term>Test species</term>
<term>Therapeutic drugs</term>
<term>Time points</term>
<term>Tissue injury</term>
<term>Tissue repair</term>
<term>Topical exposure</term>
<term>Toxic</term>
<term>Toxic chemical vapour</term>
<term>Toxic insult</term>
<term>Toxic responses</term>
<term>Toxicity</term>
<term>Toxicity studies</term>
<term>Toxicol</term>
<term>Toxicological</term>
<term>Toxicology</term>
<term>Toxicology testing</term>
<term>Transcription</term>
<term>Transcription factor</term>
<term>Transcription factors</term>
<term>Transcriptional</term>
<term>Transcriptional regulation</term>
<term>Treatment groups</term>
<term>Tumour</term>
<term>Turton</term>
<term>Typhimurium</term>
<term>Ultimate outcome</term>
<term>Uncertainty factor</term>
<term>Uncertainty factors</term>
<term>Useful tool</term>
<term>Various concentrations</term>
<term>Vivo</term>
<term>Welwyn</term>
<term>White blood cells</term>
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